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The 4 mg/mL injection strength may be used for intralesional and soft tissue administration. Doses range from mg to 4 mg injected as a single dose at the appropriate site. For soft tissue and bursal injections a dose of 2 to 4 mg is recommended. Ganglia require a dose of 1 to 2 mg. A dose of to 1 mg is used for injection into tendon sheaths. Usually employed when condition to be treated is limited to 1 or 2 sites. Dosage dependent upon degree of inflammation, size, disease state, and location of affected area. Repeat doses may be given from once every 3 to 5 days to once every 2 to 3 weeks.

It follows that the additional radiation exposure due to eating a banana lasts only for a few hours after ingestion, . the time it takes for the normal potassium content of the body to be restored by the kidneys. The EPA conversion factor, on the other hand, is based on the mean time needed for the isotopic mix of potassium isotopes in the body to return to the natural ratio after being disturbed by the ingestion of pure 40 K, which was assumed by EPA to be 30 days. [10] If the assumed time of residence in the body is reduced by a factor of ten, for example, the estimated equivalent absorbed dose due to the banana will be reduced in the same proportion.

In the pre-marketing controlled clinical studies and their open extensions (2,423 patients with median duration of follow-up of approximately 18 months), % of patients were discontinued due to adverse reactions. The most common adverse reactions that led to treatment discontinuation were: gastrointestinal disorders (%), myalgia (%), and arthralgia (%). The most commonly reported adverse reactions (incidence ≥5%) in Simvastatin controlled clinical trials were: upper respiratory infections (%), headache (%), abdominal pain (%), constipation (%), and nausea (%).

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