Iron deficiency affects more than 1 in 5 women in the US. Being deficient in essential minerals can show up in all kinds of ways but an iron deficiency can also be a blow for getting into your skinny jeans with relative ease. See, your body can’t work as efficiently to burn calories when it doesn’t have what it needs to work properly. A cup of lentils, it turns out, provides over a third of your daily iron needs. Legumes like lentils also have been shown to drive down bad cholesterol and blood pressure. That’s why they’re one of the 7 Best Foods to Eat for Raipd Weight Loss !
In subsequent phase II reactions, these activated xenobiotic metabolites are conjugated with charged species such as glutathione (GSH), sulfate , glycine , or glucuronic acid . Sites on drugs where conjugation reactions occur include carboxyl (-COOH), hydroxyl (-OH), amino (NH 2 ), and sulfhydryl (-SH) groups. Products of conjugation reactions have increased molecular weight and tend to be less active than their substrates, unlike Phase I reactions which often produce active metabolites . The addition of large anionic groups (such as GSH) detoxifies reactive electrophiles and produces more polar metabolites that cannot diffuse across membranes, and may, therefore, be actively transported.