Cases of secondary exposure to testosterone resulting in virilization of children have been reported in postmarket surveillance. Signs and symptoms of these reported cases have included enlargement of the clitoris (with surgical intervention) or the penis, development of pubic hair, increased erections and libido, aggressive behavior, and advanced bone age. In most cases with a reported outcome, these signs and symptoms were reported to have regressed with removal of the testosterone gel exposure. In a few cases, however, enlarged genitalia did not fully return to age appropriate normal size, and bone age remained modestly greater than chronological age. In some of the cases, direct contact with the sites of application on the skin of men using testosterone gel was reported. In at least one reported case, the reporter considered the possibility of secondary exposure from items such as the testosterone gel user's shirts and/or other fabric, such as towels and sheets [see WARNINGS AND PRECAUTIONS ].
I am 65, and went into menopause about 13 yrs. ago. Before that, because of our jobs as team drivers long haul, sex was few and far between, with absolutely no romance. Sex became steadily more painful after menopause, causing me to lose complete interest. I love my husband, so I keep trying, although he usually tries only once every month or 2, and always on Sat. night after drinking,dancing(VFW), & brkfst after. My GYN had me use the estrogen cream, the estrogen tablet inserted, the E-ring, Testorone cream on the skin like a patch, and none of them helped any at all. He then told me I should do the stretching exercises, which I tried, but it turned me off to sex so much, the thought of it made me sick. Wouldn't have helped much anyway, since my husband is so much larger. I still try to cringe and bear it, using Liquidbeads on the inside, and Silicone on the outside, with Vagisil to help deaden the pain itself. Have to use it to even insert the Liquidbeads applicator. Desire? How?
Another point I’d like to make for people worried about a link between high testosterone and prostate cancer is that it just doesn’t make sense. Prostate cancer becomes more prevalent in men as they age, and that’s also when their testosterone levels decline. We almost never see it in men in their peak testosterone years, in their 20s for instance. We know from autopsy studies that 8% of men in their 20s already have tiny prostate cancers, so if testosterone really made prostate cancer grow so rapidly — we used to talk about it like it was pouring gasoline on a fire — we should see some appreciable rate of prostate cancer in men in their 20s. We don’t. So, I’m no longer worried that giving testosterone to men will make their hidden cancer grow, because I’m convinced that it doesn’t happen.