A team led by Dr. Joel Finkelstein at Massachusetts General Hospital investigated testosterone and estradiol levels in 400 healthy men, 20 to 50 years of age. To control hormone levels, the researchers first gave the participants injections of a drug that suppressed their normal testosterone and estradiol production. The men were randomly assigned to 5 groups that received different amounts (from 0 to 10 grams) of a topical 1% testosterone gel daily for 16 weeks. Half of the participants were also given a drug to block testosterone from being converted to estradiol.
It’s heart wrenching to hear stories like yours. To lend some insight, I have most of my patients on estrogen blockers as well. This is something that I find necessary even though we replace to the normal range only. We recommend against GHRP-6 and all growth hormone treatment, so I cant’ speak directly to that. His testosterone dose is higher than what I would start a patient at, but it’s not exorbitant. That, however, is only part of the picture. Proper dosing is dependent upon the observation of how a patient reacts to a dose over time. So, that dose could be entirely too high for him even though I would say it is on the spectrum of normal dosing in general.