Zuclopenthixol decanoate half life

Other permanent side effects are similar to many other typical antipsychotics, namely extrapyramidal symptoms as a result of dopamine blockade in subcortical areas of the brain. This may result in symptoms similar to those seen in Parkinson's disease and include a restlessness and inability to sit still known as akathisia , a slow tremor and stiffness of the limbs. [8] Zuclopenthixol is thought to be more sedating than the related flupentixol , though possibly less likely to induce extrapyramidal symptoms than other typical depots. [5] As with other dopamine antagonists, zuclopenthixol may sometimes elevate prolactin levels; this may occasionally result in amenorrhoea or galactorrhoea in severe cases. Neuroleptic malignant syndrome is a rare but potentially fatal side effect. Any unexpected deterioration in mental state with confusion and muscle stiffness should be seen by a physician.

You may be given an injection of zuclopenthixol acetate (Clopixol Acuphase®) for a short time to get your symptoms under control, or you may be prescribed tablets to take. A long-acting, or 'depot', injection may be recommended for you once your symptoms have improved. Zuclopenthixol decanoate is a depot injection which slowly releases zuclopenthixol into your body to prevent your symptoms from coming back. It is given every 1-4 weeks. The main advantage of a depot injection is that you do not have to remember to take tablets every day.

Zuclopenthixol decanoate half life

zuclopenthixol decanoate half life

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